Endocrine Abstracts

IntroductionAccessory thyroid is defined as the presence of thyroid tissue in locations other than the normal anterior neck region between the second and fourth tracheal cartilages. It is a congenital disease caused by the abnormal migration of thyroid tissue in the embryonic stage. Lingual thyroid is the most common form of ectopic thyroid, extra lingual thyroid tissue is commonly located in the anterior cervical area, along the path of the thyroglossal...

Introduction: The HAIR-AN syndrome, which consists of hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN), is an underdiagnosed endocrinopathy.Observation: We report the case of Miss A.M., 24 years old, admitted for exploration of hyperandrogenism. Anamnesis: the patient reported polyuropolydipsic syndrome and the notion of weight gain without eating disorders, making a total of 28 kg in 6 months. This period is also marked by th...

Introduction: Kallmann syndrome (KS) is a rare disorder. It is now designated as olfactogenital dysplasia with an association between agenesis of the olfactory bulbs and hypogonadism. The association of KS with a pituitary microadenoma has not been well described in the literature.Case report: It’s a 16-year-old and 6 months, admitted for evaluation of a micropenis, he has as ATCDs an orchidopexy performed at the age of 3 years, infertility in the m...

Introduction: -Thyroid disorders can predate or develop during pregnancy. -The effects on the fetus vary depending on the disease and the drugs used for treatment. But usually, untreated or undertreated hyperthyroidism can lead to harmful complications.Case report: It’s a 26-year-old patient with a history of goiter since childhood, history of goiter in the mother; grandmother and maternal aunt. the patient is 18 weeks pregnant, the pregnancy is unp...

Introduction: Antenatal treatment with dexamethasone in pregnancies affected by congenital adrenal hyperplasias (CAH) therefore suppresses fetal androgen production and prevents virilisation of female infants. Antenatal DXM is reported to be efficacious, preventing or ameliorating virilisation in 80–85% of cases.Case report: 23-year-old patient pregnant at 6 weeks, not known of having congenital adrenal hyperplasia (CAH), concept of consanguineous m...

Introduction: Type 1 diabetes is accompanied by a high frequency of autoimmune diseases.The aim: of this study is to determine the different epidemiological, clinical, immunological and therapeutic aspects of Type 1 Diabetes in Autoimmune Polyendocrinopathy and to analyze the results obtained.Patients and methods: This is a retrospective study of 44 patients with type 1 diabetes, suffering from Autoimmune Polyendocrinopathy and fol...

Introduction: Mild autonomous cortisol secretion (MACS) is a term used to describe biochemical evidence of abnormal cortisol secretion in patients with adrenocortical adenomas (ACA), but without the classical external manifestations of overt Cushing’s syndrome (CS).Materials and Methods: In this study, we report a case of patient who presents mild autonomous cortisol secretion among incidentally discovered adrenal masses; followed in unit of the end...

Introduction: Mauriac syndrome (MS) is a rare complication of type 1 diabetes mellitus (DM1), characterized by hepatomegaly (hepatic glycogenosis), puberty and growth delay, transaminase elevation and reduction of IGF1 (insulin-like growth factor 1). MS is more common in children and adolescents with poor glycemic control.Case Report: A 17-years-old Type 1 diabetic boy was admitted for evaluation of growth retardation. He was diagnosed to have T1DM 15 ye...

Introduction: Research in the past two decades has shown that Fenugrec seeds help to lower blood glucose in patients with diabetes. Its role as an antidiabetic, by reducing fasting blood glucose levels and improved glucose tolerance in human subjects was reported Curcuminoids have been shown to improve insulin resistance, decrease glucose and insulin levels, increase adiponectin release, and reduce the levels of leptin, resistin, interleukin (IL)-6 IL-1b, and tumor necrosis fa...

Introduction: Malignant tumors, nevertheless, have been associated with extremely high circulating ACTH and cortisol levels, and short duration of symptoms of Cushing syndrome (CS) besides atypical clinical phenotype, when compared with pituitary-dependent Cushing. Identification of the source of ACTH can be challenging, as sometimes the primary lesion is not identified even after prolonged and repeated follow-upCase report: A 33-year-old woman with a hi...